Article
The association of the immune response genes to human papillomavirus-related cervical disease in a Brazilian population.
BioMed research international - 1 Jan 2013
Marangon Amanda Vansan, Guelsin Gláucia Andreia Soares, Visentainer Jeane Eliete Laguila, Borelli Sueli Donizete, Watanabe Maria Angélica Ehara, Consolaro Márcia Edilaine Lopes, Caleffi-Ferracioli Katiany Rizzieri, Rudnick Cristiane Conceição Chagas, Sell Ana Maria
Abstract excerpt
The genetic variability of the host contributes to the risk of human papillomavirus (HPV)-related cervical disease. Immune response genes to HPV must be investigated to define patients with the highest risk of developing malignant disease. The aim of this study was to investigate the association of polymorphic immune response genes, namely KIR, HLA class I and II, and single-nucleotide polymorphisms (SNPs) of...
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