Significant association between IL10-1082/-819 and TNF-308 haplotypes and the susceptibility to cervical carcinogenesis in women infected by Human papillomavirus.

doi:10.1016/j.cyto.2018.06.014

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Article

Significant association between IL10-1082/-819 and TNF-308 haplotypes and the susceptibility to cervical carcinogenesis in women infected by Human papillomavirus.

Cytokine - 1 Jan 2019

Chagas Bárbara Simas, Lima Rita de Cássia Pereira de, Paiva Júnior Sérgio de Sá Leitão, Silva Ruany Cristyne de Oliveira, Cordeiro Marcelo Nazário, Silva Neto Jacinto da Costa, Batista Marcus Vinicius de Aragão, Silva Anna Jéssica Duarte, Gurgel Ana Pavla Almeida Diniz, Freitas Antonio Carlos de

Abstract excerpt

Human papillomavirus (HPV) is responsible for high-grade cervical lesions and cervical cancer. The inflammation plays a key role in cervical cancer progression. In this context, studies propose an association between TNFα and IL10 SNPs and susceptibility to HPV infection. The present work aimed to investigate the possible association between IL10 and TNFα promoter polymorphisms and HPV infection in the cervical...

Topics

Adult
Alleles
Brazil
Carcinogenesis
Case-Control Studies
Female
Gene Frequency
Genetic Predisposition to Disease
Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Interleukin-10

Papillomaviridae

Papillomavirus Infections

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Tumor Necrosis Factor-alpha

Uterine Cervical Neoplasms

Source

Open in PubMed

Identifiers

PMID: 29935877
DOI: 10.1016/j.cyto.2018.06.014

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Significant association between IL10-1082/-819 and TNF-308 haplotypes and the susceptibility to cervical carcinogenesis in women infected by Human papillomavirus.PMID 29935877Read ↗

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