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Article

Influence of WFIKKN1 on BMP1-mediated activation of latent myostatin.

The FEBS journal - 1 Dec 2016

Szláma György, Vásárhelyi Viktor, Trexler Mária, Patthy László

Abstract excerpt

The NTR domain of WFIKKN1 protein has been shown to have significant affinity for the prodomain regions of promyostatin and latent myostatin but the biological significance of these interactions remained unclear. In view of its role as a myostatin antagonist, we tested the assumption that WFIKKN1 inhibits the release of myostatin from promyostatin and/or latent myostatin. WFIKKN1 was found to have no effect on...

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Source

Identifiers

PMID: 27782377
DOI: 10.1111/febs.13938

Genes

BMP1
WFIKKN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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