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Article

Complement factor H related proteins (CFHRs)

4 Jul 2013

Abstract excerpt

Factor H related proteins comprise a group of five plasma proteins: CFHR1, CFHR2, CFHR3, CFHR4 and CFHR5, and each member of this group binds to the central complement component C3b. Mutations, genetic deletions, duplications or rearrangements in the individual CFHR genes are associated with a number of diseases including atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathies (C3 glomerulonephritis...

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PMID: 23830046
DOI: 10.1016/j.molimm.2013.06.001

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