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Identification and validation of candidate epigenetic biomarkers in lung adenocarcinoma

26 Oct 2016

Abstract excerpt

Lung cancer is the number one cause of cancer-related deaths worldwide. DNA methylation is an epigenetic mechanism that regulates gene expression, and disease-specific methylation changes can be targeted as biomarkers. We have compared the genome-wide methylation pattern in tumor and tumor-adjacent normal lung tissue from four lung adenocarcinoma (LAC) patients using DNA methylation microarrays and identified 74...

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PMID: 27782156
DOI: 10.1038/srep35807

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