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Genome-wide DNA methylation profiling reveals novel epigenetic signatures in squamous cell lung cancer

23 Nov 2017

Abstract excerpt

BACKGROUND: Epigenetic alterations are strongly associated with the development of cancer. The aim of this study was to identify epigenetic pattern in squamous cell lung cancer (LUSC) on a genome-wide scale. RESULTS: Here we performed DNA methylation profiling on 24 LUSC and paired non-tumor lung (NTL) tissues by Illumina Human Methylation 450 K BeadArrays, and identified 5214 differentially methylated probes. By...

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PMID: 29169318
DOI: 10.1186/s12864-017-4223-3

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