Article
Genome-scale analysis of DNA methylation in lung adenocarcinoma and integration with mRNA expression.
Genome research - 1 Jul 2012
Selamat Suhaida A, Chung Brian S, Girard Luc, Zhang Wei, Zhang Ying, Campan Mihaela, Siegmund Kimberly D, Koss Michael N, Hagen Jeffrey A, Lam Wan L, Lam Stephen, Gazdar Adi F, Laird-Offringa Ite A
Abstract excerpt
Lung cancer is the leading cause of cancer death worldwide, and adenocarcinoma is its most common histological subtype. Clinical and molecular evidence indicates that lung adenocarcinoma is a heterogeneous disease, which has important implications for treatment. Here we performed genome-scale DNA methylation profiling using the Illumina Infinium HumanMethylation27 platform on 59 matched lung...
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