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Article

Genomewide DNA methylation analysis identifies novel methylated genes in non-small-cell lung carcinomas.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2013

Carvalho Rejane Hughes, Hou Jun, Haberle Vanja, Aerts Joachim, Grosveld Frank, Lenhard Boris, Philipsen Sjaak

Abstract excerpt

INTRODUCTION: DNA methylation is part of the epigenetic regulatory mechanism present in all normal cells. It is tissue-specific and stably maintained throughout development, but often abnormally changed in cancer. Non-small-cell lung carcinoma (NSCLC) is the most deadly type of cancer, involving different tumor subtypes. This heterogeneity is a challenge for correct diagnosis and patient treatment. The stability...

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PMID: 23524404
DOI: 10.1097/JTO.0b013e3182863ed2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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