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Identification of a panel of sensitive and specific DNA methylation markers for lung adenocarcinoma

29 Oct 2007

Abstract excerpt

BACKGROUND: Lung cancer is the number one cancer killer of both men and women in the United States. Three quarters of lung cancer patients are diagnosed with regionally or distantly disseminated disease; their 5-year survival is only 15%. DNA hypermethylation at promoter CpG islands shows great promise as a cancer-specific marker that would complement visual lung cancer screening tools such as spiral CT,...

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PMID: 17967182
DOI: 10.1186/1476-4598-6-70

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