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Article

Role of Fibulin 3 in Aging‐Related Joint Changes and Osteoarthritis Pathogenesis in Human and Mouse Knee Cartilage

25 Oct 2016

Abstract excerpt

Objective The EFEMP1 gene encoding fibulin 3 is specifically expressed in the superficial zone (SZ) of articular cartilage. The aims of this study were to examine the expression patterns of fibulin 3 in the knee joints during aging and during osteoarthritis (OA) and to determine the role of fibulin 3 in the pathogenesis of OA. Methods Immunohistochemical analysis was performed on normal and OA knee cartilage...

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PMID: 27780308
DOI: 10.1002/art.39963

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