Article
Fibroblast growth factor receptor 3 is a negative regulator of bone growth.
Cell - 22 Mar 1996
Deng C, Wynshaw-Boris A, Zhou F, Kuo A, Leder P
Abstract excerpt
Endochondral ossification is a major mode of bone that occurs as chondrocytes undergo proliferation, hypertrophy, cell death, and osteoblastic replacement. We have identified a role for fibroblast growth factor receptor 3 (FGFR-3) in this process by disrupting the murine Fgfr-3 gene to produce se...
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