Article
Increasing insulin resistance accentuates the effect of triglyceride-associated loci on serum triglycerides during 5 years.
Journal of lipid research - 1 Dec 2016
Justesen Johanne M, Andersson Ehm A, Allin Kristine H, Sandholt Camilla H, Jørgensen Torben, Linneberg Allan, Jørgensen Marit E, Hansen Torben, Pedersen Oluf, Grarup Niels
Abstract excerpt
Blood concentrations of triglycerides are influenced by genetic factors as well as a number of environmental factors, including adiposity and glucose homeostasis. The aim was to investigate the association between a serum triglyceride weighted genetic risk score (wGRS) and changes in fasting serum triglyceride level over 5 years and to test whether the effect of the wGRS was modified by 5 year changes of...
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