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Article

Triglyceride-Increasing Alleles Associated with Protection against Type-2 Diabetes.

PLoS genetics - 1 May 2015

Klimentidis Yann C, Chougule Akshay, Arora Amit, Frazier-Wood Alexis C, Hsu Chiu-Hsieh

Abstract excerpt

Elevated plasma triglyceride (TG) levels are an established risk factor for type-2 diabetes (T2D). However, recent studies have hinted at the possibility that genetic risk for TG may paradoxically protect against T2D. In this study, we examined the association of genetic risk for TG with incident T2D, and the interaction of baseline TG with TG genetic risk on incident T2D in 13,247 European-Americans (EA) and...

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Source

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Identifiers

PMID: 26020539
DOI: 10.1371/journal.pgen.1005204
PMCID: PMC4447354

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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