Article
The effect of GWAS identified BMI loci on changes in body weight among middle-aged Danes during a five-year period.
Obesity (Silver Spring, Md.) - 1 Mar 2014
Sandholt C H, Allin K H, Toft U, Borglykke A, Ribel-Madsen R, Sparso T, Justesen J M, Harder M N, Jørgensen T, Hansen T, Pedersen O
Abstract excerpt
OBJECTIVE: Genome-wide association studies have identified genetic variants associating with BMI, however, it is un-clarified whether the same variants also influence body weight fluctuations. METHODS: Among 3,982 adult individuals that attended both a baseline and a five-year follow-up examination in the Danish Inter99 intervention study, a genetic risk score (GRS) was constructed based on 30 BMI variants to...
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