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Article

Interaction of Insulin Resistance and Related Genetic Variants With Triglyceride-Associated Genetic Variants.

Circulation. Cardiovascular genetics - 1 Apr 2016

Klimentidis Yann C, Arora Amit

Abstract excerpt

BACKGROUND: Several studies suggest that some triglyceride-associated single-nucleotide polymorphisms (SNPs) have pleiotropic and opposite effects on glycemic traits. This potentially implicates them in pathways such as de novo lipogenesis, which is presumably upregulated in the context of insulin resistance. We therefore tested whether the association of triglyceride-associated SNPs with triglyceride levels...

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Topics

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Share to Genetic Predisposition to Disease
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Insulin Resistance

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to Triglycerides

Source

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Identifiers

PMID: 26850992
DOI: 10.1161/CIRCGENETICS.115.001246
PMCID: PMC4838530

Genes

ARL15
CILP2
GCKR
IRS1
LRPAP1
PIGV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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