Article
Polygenic Risk of Hypertriglyceridemia Is Modified by BMI.
International journal of molecular sciences - 30 Aug 2022
Esteve-Luque Virginia, Fanlo-Maresma Marta, Padró-Miquel Ariadna, Corbella Emili, Rivas-Regaira Maite, Pintó Xavier, Candás-Estébanez Beatriz
Abstract excerpt
Background: Genetic risk scores (GRSs) have partially improved the understanding of the etiology of moderate hypertriglyceridemia (HTG), which until recently was mainly assessed by secondary predisposing causes. The main objective of this study was to assess whether this variability is due to the interaction between clinical variables and GRS. Methods: We analyzed 276 patients with suspected polygenic HTG. An...
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