Article
Common functional variants of APOA5 and GCKR accumulate gradually in association with triglyceride increase in metabolic syndrome patients.
Molecular biology reports - 1 Feb 2012
Hadarits Ferenc, Kisfali Péter, Mohás Márton, Maász Anita, Duga Balázs, Janicsek Ingrid, Wittmann István, Melegh Béla
Abstract excerpt
The common functional variants of the apolipoprotein A5 (APOA5) and the glucokinase regulatory protein genes (GCKR) have been shown to associate with increased fasting triglyceride (TG) levels. Albeit the basic association has been extensively investigated in several populations of different origin, less is known about quantitative traits of them. In our study accumulation rates of four APOA5 (T-1131, IVS3 +...
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