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Article

A methodology for multivariate phenotype-based genome-wide association studies to mine pleiotropic genes.

BMC systems biology - 1 Jan 2011

Park Sung Hee, Lee Ji Young, Kim Sangsoo

Abstract excerpt

BACKGROUND: Current Genome-Wide Association Studies (GWAS) are performed in a single trait framework without considering genetic correlations between important disease traits. Hence, the GWAS have limitations in discovering genetic risk factors affecting pleiotropic effects. RESULTS: This work reports a novel data mining approach to discover patterns of multiple phenotypic associations over 52 anthropometric and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22784570
DOI: 10.1186/1752-0509-5-S2-S13
PMCID: PMC3287479

Genes

TRPM3
BCL2
NAV1
NRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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