Article
ADAMTS-1 Is Found in the Nuclei of Normal and Tumoral Breast Cells
20 Oct 2016
Abstract excerpt
Proteins secreted in the extracellular matrix microenvironment (ECM) by tumor cells are involved in cell adhesion, motility, intercellular communication and invasion. The tumor microenvironment is expansively modified and remodeled by proteases, resulting in important changes in both cell-cell and cell-ECM interactions and in the generation of new signals from the cell surface. Metalloproteinases belonging to the...
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