Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dysregulated Expression of Adamalysin-Thrombospondin Genes in Human Breast Carcinoma

1 Apr 2004

Abstract excerpt

The adamalysin-thrombospondin (ADAMTS) proteinases are a relatively newly described branch of the metzincin family that contain metalloproteinase, disintegrin, and thrombospondin motifs. They have been implicated in various cellular events, including cleavage of proteoglycans, extracellular matrix degradation, inhibition of angiogenesis, gonadal development, and organogenesis. However, in many cases, their normal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Coagulation, Bradykinin, Polyphosphates, and Angioedema
Share to Protease and Inhibitor Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15073121
DOI: 10.1158/1078-0432.ccr-0398-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dysregulated Expression of Adamalysin-Thrombospondin Genes in Human Breast CarcinomaPMID 15073121Read ↗

Expression of ADAM‐9 mRNA and protein in human breast cancerSemantic proximity Read ↗

ADAMs and ADAMTSs in cancerSemantic proximity Read ↗

ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistanceSemantic proximity Read ↗

The roles of ADAMTS metalloproteinases in tumorigenesis and metastasisSemantic proximity Read ↗

Emerging roles of ADAM and ADAMTS metalloproteinases in cancerSemantic proximity Read ↗

Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen‐1 and nidogen‐2Semantic proximity Read ↗

ADAMTS5 modulates breast cancer development as a diagnostic biomarker and potential tumor suppressor, regulating by BAIAP2-AS1, VTI1B, CRNDE, and hsa-miR-135b-3p: integrated systems biology and experimental approachSemantic proximity Read ↗

The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?Semantic proximity Read ↗

ADAMs in cancer cell proliferation and progressionSemantic proximity Read ↗

ADAM Proteins- Therapeutic Potential in CancerSemantic proximity Read ↗

Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin motifs in non-neoplastic diseasesSemantic proximity Read ↗

Expression of Members of the Novel Membrane Linked Metalloproteinase Family ADAM in Cells Derived from a Range of Haematological MalignanciesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.