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Article

Atypical localization of membrane type 1‐matrix metalloproteinase in the nucleus is associated with aggressive features of hepatocellular carcinoma

11 Jan 2007

Abstract excerpt

Membrane type 1-matrix metalloproteinase (MT1-MMP) is a versatile proteinase and recent studies indicated it could be internalized. Our earlier study found that it is overexpressed in hepatocellular carcinoma (HCC) and could promote intrahepatic metastasis. The present study was conducted to examine its subcellular localization and its clinicopathological significance in HCC after curative partial hepatectomy....

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PMID: 17219425
DOI: 10.1002/mc.20270

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