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Article

Modelling Mutation Spectra of Human Carcinogens Using Experimental Systems.

Basic & clinical pharmacology & toxicology - 1 Sept 2017

Zhivagui Maria, Korenjak Michael, Zavadil Jiri

Abstract excerpt

Mutation spectra in cancer genomes provide information on the disease aetiology and the causality underlying the evolution and progression of cancer. Genome-wide mutation patterns reflect the effects of mutagenic insults and can thus reveal past carcinogen-specific exposures and inform hypotheses on the causative factors for specific cancer types. To identify mutation profiles in human cancers, single-gene...

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PMID: 27754614
DOI: 10.1111/bcpt.12690

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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