Article
The Group A Streptococcus serotype M2 pilus plays a role in host cell adhesion and immune evasion.
Molecular microbiology - 1 Jan 2017
Tsai Jia-Yun C, Loh Jacelyn M S, Clow Fiona, Lorenz Natalie, Proft Thomas
Abstract excerpt
Group A Streptococcus (GAS), or Streptococcus pyogenes, is a human pathogen that causes diseases ranging from skin and soft tissue infections to severe invasive diseases, such as toxic shock syndrome. Each GAS strain carries a particular pilus type encoded in the variable fibronectin-binding, collagen-binding, T antigen (FCT) genomic region. Here, we describe the functional analysis of the serotype M2 pilus...
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