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Article

T4 Pili Promote Colonization and Immune Evasion Phenotypes of Nonencapsulated M4 Streptococcus pyogenes.

mBio - 21 Jul 2020

Chen Yi-Hsuan, Li Shao-Hui, Yang Yao-Cheng, Hsu Shu-Hao, Nizet Victor, Chang Yung-Chi

Abstract excerpt

Streptococcus pyogenes (group A Streptococcus [GAS]) is an important human pathogen causing a broad spectrum of diseases and associated with significant global morbidity and mortality. Almost all GAS isolates express a surface hyaluronic acid capsule, a virulence determinant that facilitates host colonization and impedes phagocyte killing. However, recent epidemiologic surveillance has reported a sustained...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32694142
DOI: 10.1128/mBio.01580-20
PMCID: PMC7374061

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