Article
Contribution of pilus type 2b to invasive disease caused by a Streptococcus agalactiae ST-17 strain.
BMC microbiology - 3 Jul 2017
Lazzarin Maddalena, Mu Rong, Fabbrini Monica, Ghezzo Claudia, Rinaudo C Daniela, Doran Kelly S, Margarit Immaculada
Abstract excerpt
BACKGROUND: Group B Streptococcus (GBS) is a major cause of invasive disease especially in neonates. In GBS three structurally distinct pilus polymers have been identified as important virulence factors and promising vaccine candidates. The vast majority of Group B Streptococci belonging to the hypervirulent serotype III ST-17 lineage bear pilus types 1 and 2b. The purpose of this study was to investigate the...
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