Molecular and genomic characterization of pathogenic traits of group A Streptococcus pyogenes

doi:10.2183/pjab.91.539

Article

Molecular and genomic characterization of pathogenic traits of group A Streptococcus pyogenes

1 Jan 2015

Abstract excerpt

Group A streptococcus (GAS) or Streptococcus pyogenes causes various diseases ranging from self-limiting sore throat to deadly invasive diseases. The genome size of GAS is 1.85-1.9 Mb, and genomic rearrangement has been demonstrated. GAS possesses various surface-associated substances such as hyaluronic capsule, M proteins, and fibronectin/laminin/immunoglobulin-binding proteins. These are related to the...

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