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Article

Molecular architecture of Streptococcus pneumoniae TIGR4 pili.

The EMBO journal - 16 Dec 2009

Hilleringmann Markus, Ringler Philippe, Müller Shirley A, De Angelis Gabriella, Rappuoli Rino, Ferlenghi Ilaria, Engel Andreas

Abstract excerpt

Although the pili of Gram-positive bacteria are putative virulence factors, little is known about their structure. Here we describe the molecular architecture of pilus-1 of Streptococcus pneumoniae, which is a major cause of morbidity and mortality worldwide. One major (RrgB) and two minor components (RrgA and RrgC) assemble into the pilus. Results from TEM and scanning transmission EM show that the native pili...

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Identifiers

PMID: 19942854
DOI: 10.1038/emboj.2009.360
PMCID: PMC2797065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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