Article
Comparative genomics analysis of a series of Yarrowia lipolytica WSH-Z06 mutants with varied capacity for α-ketoglutarate production.
Journal of biotechnology - 10 Dec 2016
Zeng Weizhu, Fang Fang, Liu Song, Du Guocheng, Chen Jian, Zhou Jingwen
Abstract excerpt
Yarrowia lipolytica is one of the most intensively investigated α-ketoglutaric acid (α-KG) producers, and metabolic engineering has proven effective for enhancing production. However, regulation of α-KG metabolism remains poorly understood. Genetic engineering of new strains is accompanied by potential safety concerns in some countries and regions. A series of mutants with varied capacity for α-KG production were...
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