Phenotyping transcription factors-related genotypes in Y. lipolytica across a range of industrially relevant process parameters and chemical stress conditions.

Abstract excerpt

One of the factors contributing to “the death valley” in biotech process transfer is an assumption that once a synthetic trait is successfully introduced and optimized in a microbial host, the resulting strain attains “industrial potential”. In practice, most engineered strains lack the robustness required to perform sufficiently in the demanding conditions of industrial bioprocesses. Stress tolerance is a...

Topics

• Yarrowia
• Transcription Factors
• Genotype
• Phenotype
• Stress, Physiological