Article
Synthesis of alpha-ketoglutaric acid by Yarrowia lipolytica yeast grown on ethanol.
Applied microbiology and biotechnology - 1 Feb 2000
Chernyavskaya O G, Shishkanova N V, Il'chenko A P, Finogenova T V
Abstract excerpt
The ability of yeast to synthesize alpha-ketoglutaric acid (KGA) from ethanol has been studied. Thiamine-auxotrophic yeasts of different genera and species may be able to produce KGA; the main condition of synthesis is growth limitation by thiamine. Using a model culture, mutant Yarrowia lipolytica N 1, the principal conditions affecting KGA oversynthesis were identified. These were: thiamine concentration in...
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