Article
Clock gene homologs lin-42 and kin-20 regulate circadian rhythms in C. elegans.
Scientific reports - 5 Jun 2024
Lamberti Melisa L, Spangler Rebecca K, Cerdeira Victoria, Ares Myriam, Rivollet Lise, Ashley Guinevere E, Coronado Andrea Ramos, Tripathi Sarvind, Spiousas Ignacio, Ward Jordan D, Partch Carrie L, Bénard Claire Y, Goya M Eugenia, Golombek Diego A
Abstract excerpt
Circadian rhythms are endogenous oscillations in nearly all organisms, from prokaryotes to humans, allowing them to adapt to cyclical environments for close to 24 h. Circadian rhythms are regulated by a central clock, based on a transcription-translation feedback loop. One important protein in the central loop in metazoan clocks is PERIOD, which is regulated in part by Casein kinase 1ε/δ (CK1ε/δ) phosphorylation....
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