Article
Clinical significance of the single nucleotide polymorphism TLR2 R753Q in heart transplant recipients at risk for cytomegalovirus disease.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Nov 2016
Schneider Martina, Matiqi Teresa, Kundi Michael, Rieder Franz J J, Andreas Martin, Strassl Robert, Zuckermann Andreas, Jungbauer Christof, Steininger Christoph
Abstract excerpt
BACKGROUND: The toll-like receptor 2 (TLR2) is a significant component of innate immunity against cytomegalovirus (CMV) infection but information on the clinical significance of the single nucleotide polymorphism (SNP) (R753Q) is conflicting. OBJECTIVES: The inconsistent observations of the immunological and clinical significance of the TLR2 R753Q polymorphism for CMV infection indicates the influence of...
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