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Article

Relationship between toll-like receptor 2 Arg677Trp and Arg753Gln and toll-like receptor 4 Asp299Gly polymorphisms and cytomegalovirus infection.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Aug 2014

Jabłońska Agnieszka, Paradowska Edyta, Studzińska Mirosława, Suski Patrycja, Nowakowska Dorota, Wiśniewska-Ligier Małgorzata, Woźniakowska-Gęsicka Teresa, Wilczyński Jan, Leśnikowski Zbigniew J

Abstract excerpt

OBJECTIVES: The association among specific single-nucleotide polymorphisms (SNPs) in TLR2 (Arg677Trp, Arg753Gln) and TLR4 (Asp299Gln) and human cytomegalovirus (CMV) infection was studied in infants and adults. METHODS: The TLR2 and TLR4 polymorphisms were genotyped in 151 patients with CMV infections and in 78 unrelated healthy individuals. Genotyping was performed by restriction fragment length polymorphism...

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Identifiers

PMID: 24813591
DOI: 10.1016/j.ijid.2014.04.001

Genes

TLR2
TLR4

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