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Article

The LGI1-ADAM22 protein complex in synaptic transmission and synaptic disorders.

Neuroscience research - 1 Mar 2017

Fukata Yuko, Yokoi Norihiko, Miyazaki Yuri, Fukata Masaki

Abstract excerpt

Physiological functioning of the brain requires fine-tuned synaptic transmission, and its dysfunction causes various brain disorders such as autism, dementia, and epilepsy. It is therefore extremely important to identify and characterize key regulators of synaptic function. In particular, disease-related synaptic proteins, such as autism-related neurexin-neuroligin and psychiatric disorder-related NMDA receptor,...

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Source

Identifiers

PMID: 27717669
DOI: 10.1016/j.neures.2016.09.011

Genes

LGI1
ADAM22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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