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Article

Biological characterization of ADAM22 variants reveals the importance of a disintegrin domain sequence in cell surface expression.

Journal of receptor and signal transduction research - 1 Apr 2010

Sagane Koji, Sugimoto Hachiro, Akaike Akinori

Abstract excerpt

ADAM metallopeptidase domain 22 (ADAM22) is a neuronal membrane-spanning protein that is a potential receptor for leucine-rich, glioma-inactivated 1 (LGI1), and leucine-rich repeat LGI family, member 4 (LGI4). Several lines of study have shown a direct interaction between ADAM22 and LGI1, a mutat...

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Source

Identifiers

PMID: 20156119
DOI: 10.3109/10799891003614790

Genes

ADAM22
LGI1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20156119-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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