Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The brain-derived neurotrophic factor Val66Met polymorphism affects encoding of object locations during active navigation.

The European journal of neuroscience - 1 Jun 2017

Wegman Joost, Tyborowska Anna, Hoogman Martine, Arias Vásquez Alejandro, Janzen Gabriele

Abstract excerpt

The brain-derived neurotrophic factor (BDNF) was shown to be involved in spatial memory and spatial strategy preference. A naturally occurring single nucleotide polymorphism of the BDNF gene (Val66Met) affects activity-dependent secretion of BDNF. The current event-related fMRI study on preselected groups of 'Met' carriers and homozygotes of the 'Val' allele investigated the role of this polymorphism on encoding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain-Derived Neurotrophic Factor
Share to BDNF gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hippocampus

Share to Homozygote

Share to Mutation, Missense

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 27717213
DOI: 10.1111/ejn.13416
PMCID: PMC5484279

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The brain-derived neurotrophic factor Val66Met polymorphism affects encoding of object locations during active navigation.PMID 27717213Read ↗

The BDNF val66met polymorphism is associated with decreased use of landmarks and decreased fMRI activity in the hippocampus during virtual navigation.Semantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism is associated with reduced functional magnetic resonance imaging activity in the hippocampus and increased use of caudate nucleus-dependent strategies in a human virtual navigation task.Semantic proximity Read ↗

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.Semantic proximity Read ↗

The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli.Semantic proximity Read ↗

BDNF Val66Met polymorphism significantly affects d' in verbal recognition memory at short and long delays.Semantic proximity Read ↗

Effects of the BDNF Val66Met polymorphism and met allele load on declarative memory related neural networks.Semantic proximity Read ↗

Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks.Semantic proximity Read ↗

BDNF Val66Met gene polymorphism modulates brain activity following rTMS-induced memory impairment.Semantic proximity Read ↗

The role of the BDNF Val66Met polymorphism in individual differences in long-term memory capacity.Semantic proximity Read ↗

Functional magnetic resonance imaging of BDNF val66met polymorphism in unmedicated subjects at high genetic risk of schizophrenia performing a verbal memory task.Semantic proximity Read ↗

Effect of BDNF Val66Met polymorphism on digital working memory and spatial localization in a healthy Chinese Han population.Semantic proximity Read ↗

The brain-derived neurotrophic factor val66met polymorphism and variation in human cortical morphology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.