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Article

A High-Throughput Small Molecule Screen for C. elegans Linker Cell Death Inhibitors.

PloS one - 1 Jan 2016

Schwendeman Andrew R, Shaham Shai

Abstract excerpt

Programmed cell death is a ubiquitous process in metazoan development. Apoptosis, one cell death form, has been studied extensively. However, mutations inactivating key mammalian apoptosis regulators do not block most developmental cell culling, suggesting that other cell death pathways are likely important. Recent work in the nematode Caenorhabditis elegans identified a non-apoptotic cell death form mediating...

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PMID: 27716809
DOI: 10.1371/journal.pone.0164595
PMCID: PMC5055323

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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