Article

Non-apoptotic death of the <i>C. elegans</i> linker cell is primed by MYRF-1 activation of <i>pqn-41</i> /polyQ

2025-12-11

Abstract excerpt

Linker cell-type death (LCD) is a morphologically conserved non-apoptotic cell-death process with features resembling polyglutamine-dependent neurodegeneration. In C. elegans development, LCD eliminates the male-specific linker cell following its long-range migration. Using single-cell mRNA sequencing of migrating and dying linker cells, we identify myrf-1 , encoding a membrane-bound transcription factor implica...

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Literature Corpus work: 046f725f-7916-5ff2-8f05-e6cd7b28882d
DOI: 10.64898/2025.12.08.693091

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Non-apoptotic death of the <i>C. elegans</i> linker cell is primed by MYRF-1 activation of <i>pqn-41</i> /polyQDOI 10.64898/2025.12.08.693091Read

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