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Article

Modeling neurological diseases with induced pluripotent cells reprogrammed from immortalized lymphoblastoid cell lines.

Molecular brain - 3 Oct 2016

Fujimori Koki, Tezuka Toshiki, Ishiura Hiroyuki, Mitsui Jun, Doi Koichiro, Yoshimura Jun, Tada Hirobumi, Matsumoto Takuya, Isoda Miho, Hashimoto Ryota, Hattori Nubutaka, Takahashi Takuya, Morishita Shinichi, Tsuji Shoji, Akamatsu Wado, Okano Hideyuki

Abstract excerpt

Patient-specific induced pluripotent stem cells (iPSCs) facilitate understanding of the etiology of diseases, discovery of new drugs and development of novel therapeutic interventions. A frequently used starting source of cells for generating iPSCs has been dermal fibroblasts (DFs) isolated from skin biopsies. However, there are also numerous repositories containing lymphoblastoid B-cell lines (LCLs) generated...

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Identifiers

PMID: 27716287
DOI: 10.1186/s13041-016-0267-6
PMCID: PMC5046991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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