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Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines

8 Oct 2014

Abstract excerpt

Patient-specific induced pluripotent stem cells (iPSCs) hold great promise for many applications, including disease modeling to elucidate mechanisms involved in disease pathogenesis, drug screening, and ultimately regenerative medicine therapies. A frequently used starting source of cells for reprogramming has been dermal fibroblasts isolated from skin biopsies. However, numerous repositories containing...

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PMID: 25298370
DOI: 10.5966/sctm.2014-0121

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