Disease-specific Induced Pluripotent Stem Cells

Abstract excerpt

Although in vitro cell culture is a cornerstone of normal and pathological biomedical research, it has always been limited by the presence of artifacts, genetic and otherwise, and the requirement of using either primary or genetically modified cells to allow immortal propagation. In contrast, human embryonic stem cells, which are pluripotent and theoretically able to form any cell type, can establish more...

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