Article
Common epigenetic variation in a European population of mentally healthy young adults.
Journal of psychiatric research - 1 Dec 2016
Milnik Annette, Vogler Christian, Demougin Philippe, Egli Tobias, Freytag Virginie, Hartmann Francina, Heck Angela, Peter Fabian, Spalek Klara, Stetak Attila, de Quervain Dominique J-F, Papassotiropoulos Andreas, Vukojevic Vanja
Abstract excerpt
DNA methylation represents an important link between structural genetic variation and complex phenotypes. The study of genome-wide CpG methylation and its relation to traits relevant to psychiatry has become increasingly important. Here, we analyzed quality metrics of 394,043 CpG sites in two samples of 568 and 319 mentally healthy young adults. For 25% of all CpGs we observed medium to large common epigenetic...
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