[Somatic hypermutagenesis in immunoglobulin genes. I. Connection of somatic mutations with repeats. A statistical weighting method].

Article

[Somatic hypermutagenesis in immunoglobulin genes. I. Connection of somatic mutations with repeats. A statistical weighting method].

Molekuliarnaia biologiia - 1 Jan 2000

Solov'ev V V, Rogozin I V, Kolchanov N A

Abstract excerpt

Based on the analysis of a number of immunoglobulin genes' nucleotide sequences, it has been suggested, that somatic mutations emerge by means of imperfect duplexes correction, formed by mispairing of complementary regions of direct and inverted repeats. In the present work provides new data, con...

Topics

Animals
Base Sequence
Genes, Immunoglobulin
Humans
Molecular Sequence Data
Mutation
Repetitive Sequences, Nucleic Acid

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