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Article

Network analysis of mitonuclear GWAS reveals functional networks and tissue expression profiles of disease-associated genes.

Human genetics - 1 Jan 2017

Johnson Simon C, Gonzalez Brenda, Zhang Quanwei, Milholland Brandon, Zhang Zhengdong, Suh Yousin

Abstract excerpt

While mitochondria have been linked to many human diseases through genetic association and functional studies, the precise role of mitochondria in specific pathologies, such as cardiovascular, neurodegenerative, and metabolic diseases, is often unclear. Here, we take advantage of the catalog of human genome-wide associations, whole-genome tissue expression and expression quantitative trait loci datasets, and...

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Identifiers

PMID: 27704213
DOI: 10.1007/s00439-016-1736-9
PMCID: PMC5214989

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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