Article

Integrative analyses identify potential key genes and pathways in Keshan disease using whole-exome sequencing

2021-03-15

Abstract excerpt

Keshan disease (KD), an endemic heart disease with multifocal necrosis and replacement fibrosis of the myocardium,is still a nightmare situation for human health. However, molecular mechanism in the pathogenesis of KD remains unclear. Herein, blood samples were collected from 68 KD patients and 100 controls, and we systematically analyzed mutation profiles using whole-exome sequencing (WES). Causative genes of dil...

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Literature Corpus work: e287d124-1f9b-5e10-a93a-200532e91765
DOI: 10.1101/2021.03.12.21253491

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