Article
Polymorphisms in Toll-like receptor 3 are associated with asthma-related phenotypes in the Chinese Han patients.
International journal of immunogenetics - 1 Dec 2016
Zhang Q, Fu X L, Qian F H, Cao Q, Mao Z D, Bai J L, Du Q, Shi Y
Abstract excerpt
Toll-like receptor (TLR) 3 mediates antivirus immunity and is involved in asthma exacerbation and development. However, the genetic association between TLR3 and asthma remains unclear. This study aimed to evaluate the effects of polymorphisms within TLR3 on asthma risk and asthma-related phenotypes in the Chinese Han population. A total number of 462 unrelated adult patients with asthma and 398 healthy volunteers...
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