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Article

The Genetic Variants of Interferon Regulatory Factor-3 in Children with Asthma.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Dec 2020

Mosayyebi Solmaz, Sarac Basak Ezgi, Akel Bilgic Hayriye, Sahiner Umit Murat, Sackesen Cansın, Kalayci Omer, Karaaslan Cagatay

Abstract excerpt

Interferon Regulatory Factor-3 (IRF-3) is one of the key players in the inflammatory response mediated by the innate immune system. Although many studies have implicated a role for IRF-3 in the pathogenesis of inflammatory airway diseases, information about the possible association of IRF-3 genetic variants with asthma is scarce. We aimed to investigate the potential effects of IRF-3 polymorphisms in childhood...

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PMID: 33337935
DOI: 10.1089/jir.2020.0172

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