Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rhinovirus 16 2A Protease Affects Nuclear Localization of 3CD during Infection

29 Sept 2016

Abstract excerpt

ABSTRACT The human rhinovirus (HRV) 3C and 2A proteases (3Cproand 2Apro, respectively) are critical in HRV infection, as they are required for viral polyprotein processing as well as proteolysing key host factors to facilitate virus replication. Early in infection, 3Cprois present as its precursor 3CD, which, although the mechanism of subcellular targeting is unknown, is found in the nucleus as well as the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Respiratory viral infections research
Share to Viral gastroenteritis research and epidemiology
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27681132
DOI: 10.1128/jvi.00974-16

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rhinovirus 16 2A Protease Affects Nuclear Localization of 3CD during InfectionPMID 27681132Read ↗

Rhinovirus 3C Protease Facilitates Specific Nucleoporin Cleavage and Mislocalisation of Nuclear Proteins in Infected Host CellsSemantic proximity Read ↗

Exploitation of nuclear functions by human rhinovirus, a cytoplasmic RNA virusSemantic proximity Read ↗

Rhinovirus 2A is the predominant protease responsible for instigating the early block to gene expression encountered in infected cellsSemantic proximity Read ↗

Picornavirus 3C Proteins Intervene in Host Cell Processes through Proteolysis and Interactions with RNASemantic proximity Read ↗

Viral Proteinase Requirements for the Nucleocytoplasmic Relocalization of Cellular Splicing Factor SRp20 during Picornavirus InfectionsSemantic proximity Read ↗

The coronavirus 3CL protease: Unveiling its complex host interactions and central role in viral pathogenesisSemantic proximity Read ↗

Enteroviral 3C protease cleaves N4BP1 to impair the host inflammatory responseSemantic proximity Read ↗

Direct cleavage of human NLRP1 by enteroviral 3C protease triggers inflammasome activation in airway epitheliumSemantic proximity Read ↗

The Stress Granule Protein G3BP1 Recruits Protein Kinase R To Promote Multiple Innate Immune Antiviral ResponsesSemantic proximity Read ↗

Interaction of 2A proteinase of human rhinovirus genetic group A with eIF4E is required for eIF4G cleavage during infection.Semantic proximity Read ↗

Productive Entry Pathways of Human RhinovirusesSemantic proximity Read ↗

Heterogeneous Nuclear Ribonucleoprotein M Facilitates Enterovirus InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.