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Article

Productive Entry Pathways of Human Rhinoviruses

1 Jan 2012

Abstract excerpt

Currently, complete or partial genome sequences of more than 150 human rhinovirus (HRV) isolates are known. Twelve species A use members of the low-density lipoprotein receptor family for cell entry, whereas the remaining HRV-A and all HRV-B bind ICAM-1. HRV-Cs exploit an unknown receptor. At least all A and B type viruses depend on receptor-mediated endocytosis for infection. In HeLa cells, they are internalized...

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PMID: 23227049
DOI: 10.1155/2012/826301

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