Article
PON1 gene polymorphisms in patients with chronic obstructive pulmonary disease.
Journal of clinical pathology - 1 Nov 2018
Grdić Rajković Marija, Popović-Grle Sanja, Vukić Dugac Andrea, Rogić Dunja, Rako Ivana, Radić Antolić Margareta, Beriša Mirela, Rumora Lada
Abstract excerpt
AIMS: Chronic obstructive pulmonary disease (COPD) is characterised with oxidative stress. Paraoxonase 1 (PON1) is an enzyme, coded by PON1 gene, with distinctive antiatherogenic and antioxidative roles. We aimed to investigate the frequencies of Q192R, L55M and -108C>T polymorphisms and association of those polymorphisms with paraoxonase and arylesterase activities in patients with COPD. METHODS: PON1 genotype...
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